QuickView for sister chromatid biorientation (biogroup)

1. Cystic fibrosis bronchial epithelial cells expressing mutant CFTR and treated with small molecules
2. Esophageal epithelium from NRF2 mutant mice with induced gastric and duodenal reflux
3. Spatio-temporal transcriptome of the human brain
4. Macrophages activated alternatively with IL-4 or classically with IFN-gamma and TNF
5. Dendritic cells and monocytes treated with different vaccines and TLR ligands

1. Pericentromeric sister chromatid cohesion promotes kinetochore biorientation.
2. Pericentric chromatin loops function as a nonlinear spring in mitotic force balance.
3. S. cerevisiae chromosomes biorient via gradual resolution of syntely between S phase and anaphase.
4. Uncoordinated loss of chromatid cohesion is a common outcome of extended metaphase arrest.
5. Budding yeast mitotic chromosomes have an intrinsic bias to biorient on the spindle.

There were no clinical trials for sister chromatid biorientation