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QuickView for ligand-gated ion channel activity (biogroup)


Body Atlas

Most Correlated Tissues

  1. Pons
  2. Prefrontal cortex
  3. Myometrium
  4. Globus pallidus
  5. Cingulate cortex
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Disease Atlas

Most Correlated Diseases

  1. Pyloric ulcer
  2. Vesicular stomatitis Indiana virus disease
  3. Helicobacter pylori gastrointestinal tract infection
  4. Toxoplasmosis
  5. Nerve injury
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Pharmaco Atlas

Most Correlated Compounds

  1. tizanidine
  2. OTS-167
  3. CGP 60474
  4. flavopiridol
  5. A 443654
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. TDP2
  2. PPP2R2C
  3. NCL
  4. NR5A1
  5. PPRC1
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Adipocyte ASC cells treated with small molecule perturbagens
  2. L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
  3. L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
  4. L1000 CMAP - Skeletal muscle SKL.C cells treated with small molecule perturbagens
  5. L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. In search of allosteric modulators of a7-nAChR by solvent density guided virtual screening.
  2. Effects of protostane-type triterpenoids on the 5-HT3A receptor-mediated ion current in Xenopus oocy…
  3. Effects of triterpenoids from Poria cocos Wolf on the serotonin type 3A receptor-mediated ion curren…
  4. Effects of ginsenosides on GABA(A) receptor channels expressed in Xenopus oocytes.
  5. Glycine and gamma-aminobutyric acid(A) receptor function is enhanced by inhaled drugs of abuse.
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Clinical Trials

Most Relevant Clinical Trials

  1. Excitatory Amino Acids and Activated Microglia After Traumatic Brain Injury: a (R)-[11C]PK11195 PET …
  2. SB705498 Proof of Concept Chamber Challenge in Subjects With Non Allergic Rhinitis
  3. Evaluation of a Novel Positron Emission Tomography (PET Radiotracer for TARP Gamma-8
  4. Effects of Transdermal Nicotine on Response Inhibition to Emotional Cues in Schizophrenia
  5. Central and Peripheral Nervous System Changes as Markers of Disease Progression in Multiple Sclerosi…
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