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MAP kinase kinase activity
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Summary
General Info
Body Atlas
Most Correlated Tissues
Breast tissue
Synovial membrane
Adipose tissue
Bone marrow
Ovary
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Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Poisoning by drug AND/OR medicinal substance
Sepsis due to coagulase negative Staphylococcus
Toxic nephropathy
Antiphospholipid syndrome
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Pharmaco Atlas
Most Correlated Compounds
KW 2449
CG-930
A 443654
ARQ 197
PF 573228
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Knockdown Atlas
Most Correlated Gene Perturbations
PCDH11X
FBP2
LCP2
CYP2C19
FUBP3
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Curated Studies
Most Correlated Studies
L1000 CMAP - Neuronal NEU cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Skeletal muscle SKL.C cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Neural progenitor NPC cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Dihydrotestosterone and estradiol-17beta mutually neutralize their inhibitory effects on human vascu…
High glucose blocks the effects of estradiol on human vascular cell growth: differential interaction…
Mitogen-activated protein kinase kinase inhibitor suppresses cyclin B1 synthesis and reactivation of…
Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular …
Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan, inhibits MAP kinases and AP-1 activation…
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Clinical Trials
Most Relevant Clinical Trials
P38 Mitogen-activated Protein (Map) Kinase Inhibitor (SB-681323)Study In Patients With Neuropathic P…
Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With…
Evaluation of a Promising New Combination of Protein Kinase Inhibitors on Organotypic Cultures of Hu…
A PET Study of the Effects of p38 MAP Kinase Inhibitor, VX-745, on Amyloid Plaque Load in Alzheimer'…
Clinical Pharmacology of p38 MAP Kinase Inhibitor, VX-745, in Mild Cognitive Impairment Due to Alzhe…
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