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negative regulation of T cell proliferation
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Amygdala
Parietal lobe
Corpus callosum
Testes
Caudate
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Disease Atlas
Most Correlated Diseases
Vesicular stomatitis Indiana virus disease
Disease due to Togaviridae
Peritoneal foreign body
Contact dermatitis
Stachybotryotoxicosis
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Pharmaco Atlas
Most Correlated Compounds
N-(5-(4-bromophenyl)-6-(2-(5-bromopyrimidin-2-yloxy)ethoxy)pyrimidin-4-yl)-N'-propylaminosulfonamide
CGP 60474
OTS-167
tizanidine
flavopiridol
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Knockdown Atlas
Most Correlated Gene Perturbations
DROSHA
PPP2R2C
GRB14
NR5A1
PPRC1
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Curated Studies
Most Correlated Studies
Tumor formation by ATG5 KO cells
Carotid arteries from atherogenic ApoE knockout mice with carotid artery injury
Glomerulonephrotic and healthy tissue from C57BL6.MRLc1 congenic mice
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
CTLA-4 gene polymorphism +49 A/G contributes to genetic susceptibility to two infection-related canc…
Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kin…
Tyrosine phosphatase SHP-2 binding to CTLA-4: absence of direct YVKM/YFIP motif recognition.
MAb 18D3 triggering of integrin beta 1 will prevent but not terminate proliferation of human T cells…
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Clinical Trials
Most Relevant Clinical Trials
Cetuximab Plus Dalpicilib in Patients With HPV Negative, PD-1 Resistant R/M HNSCC
Transplant T CD4+ CCR7+ In Hematopoietic Stem Cells Allograft
Effect of Different Therapeutic Strategies on Regulatory T Cells in Kidney Transplantation
Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T…
B Cell Maturation Antigen Targeted CAR-T Cells in Treatment With Relapsed and Refractory Multiple My…
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