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QuickView for MHC class I peptide loading complex (biogroup)


Body Atlas

Most Correlated Tissues

  1. Tonsil
  2. Thymus gland
  3. Small intestine
  4. Lymph nodes
  5. Cerebellar vermis
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Disease Atlas

Most Correlated Diseases

  1. Disease due to Orthopoxvirus
  2. Tularemia
  3. Infection by Encephalitozoon cuniculi
  4. Multiple organ dysfunction syndrome
  5. Viral carditis
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Pharmaco Atlas

Most Correlated Compounds

  1. Carrageenan
  2. Fatty Acids
  3. Interferon alpha-2
  4. Rebif
  5. TGFB2 protein, human
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. Pdgfrb
  2. TIRAP
  3. ATF7
  4. GREB1
  5. CHMP2A
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Curated Studies

Most Correlated Studies

  1. OMIM - Immunodeficiency disorder
  2. OMIM - Bare lymphocyte syndrome
  3. OMIM - Congenital disorder
  4. Retinal pigment epithelium gene expression in response to 6 and 42hr treatment with TGF or TNFa
  5. Immune cells and spleens from mice infected with different viral vector platforms
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Literature

Most Relevant Literature

  1. Aggregate formation by ERp57-deficient MHC class I peptide-loading complexes.
  2. Tapasin and ERp57 form a stable disulfide-linked dimer within the MHC class I peptide-loading comple…
  3. Construction and destruction of MHC class I in the peptide-loading complex.
  4. Molecular architecture of the TAP-associated MHC class I peptide-loading complex.
  5. Distinct functions for the glycans of tapasin and heavy chains in the assembly of MHC class I molecu…
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Clinical Trials

Most Relevant Clinical Trials

  1. Immunization With HIV-1 Peptides in Adjuvant for Treatment of Patients With Chronic HIV-infection
  2. Natural Dendritic Cells for Immunotherapy of Chemo-naive Metastatic Castration-resistant Prostate Ca…
  3. Early High-Dose Vitamin D and Residual β-Cell Function in Pediatric Type 1 Diabetes
  4. Valuation of the Safety and Efficacy of Combination of Cryoablation and Dendric Cell/Cytokine-induce…
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