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QuickView for regulation of histone H4 acetylation (biogroup)


Body Atlas

Most Correlated Tissues

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Disease Atlas

Most Correlated Diseases

  1. Hemorrhagic shock
  2. Microbial culture finding
  3. Bacterial infection due to Bacillus
  4. Pyloric ulcer
  5. Injury of eye region
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Pharmaco Atlas

Most Correlated Compounds

  1. valrubicin
  2. N-(2-aminophenyl)-4-((4-pyridin-3-ylpyrimidin-2-ylamino)methyl)benzamide
  3. ACY 1215
  4. SB939 compound
  5. PXD101
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. TCIRG1
  2. PPP2R2C
  3. NOP2
  4. NR5A1
  5. hsa-miR-365a-3p
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Skeletal muscle SKL.C cells treated with small molecule perturbagens
  2. Induction of pluripotency in mouse somatic cells with novel factors
  3. L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
  4. L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
  5. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature

Most Relevant Literature

  1. Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.
  2. Xbp1-mediated histone H4 deacetylation contributes to DNA double-strand break repair in yeast.
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Clinical Trials

Most Relevant Clinical Trials

  1. Epigenetic Regulation of BDNF in Major Depression
  2. Phase I-II Study of Vorinostat, Paclitaxel, and Bevacizumab in Metastatic Breast Cancer
  3. LBH589 (Panobinostat) for the Treatment of Myelofibrosis
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