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protein splicing
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Summary
General Info
Body Atlas
Most Correlated Tissues
Breast tissue
Liver
Stomach
Kidney
Skeletal muscle
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Disease Atlas
Most Correlated Diseases
Multiple organ dysfunction syndrome
Waardenburg's syndrome
Brachydactyly
Coloboma of eye
Holoprosencephaly sequence
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Pharmaco Atlas
Most Correlated Compounds
compound 30
Inhba protein, mouse
Gonadotropins, Equine
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Amino Acids
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Knockdown Atlas
Most Correlated Gene Perturbations
CAVIN1
IL23R
TMEFF2
GHRHR
DUT
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Curated Studies
Most Correlated Studies
L1000 CMAP Colorectal cancer HT 29 cells with gene overexpression perturbations
Sinoatrial node-like cells differentiated from H9 hPSCs with dual SHOX2 and MYH6 gene knockin
L1000 CMAP Prostate cancer PC3 cells with gene overexpression perturbations (1 of 2)
Hippocampus and liver gene expression after arachidonate-rich diets
Gene expression profile in isolated E13 gonadal somatic support cells and E13 gonads
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Literature
Most Relevant Literature
Protein trans-splicing of an atypical split intein showing structural flexibility and cross-reactivi…
Chemical bypass of intein-catalyzed N-S acyl shift in protein splicing.
Mechanism of C-terminal intein cleavage in protein splicing from QM/MM molecular dynamics simulation…
Structural basis for protein trans-splicing by a bacterial intein-like domain--protein ligation with…
Biological applications of protein splicing.
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Clinical Trials
Most Relevant Clinical Trials
Sodium Channel Splicing in Heart Failure Trial
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and C…
Sodium Channel Splicing in Obstructive Sleep Apnea (SOCS-OSA)
Validation of Therapeutic Efficacy Targeting the Splicing Variants in Cystic Fibrosis and CFTR Patho…
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic …
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