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pro-B cell differentiation
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Thymus gland
Hematopoietic stem cell of bone marrow
Endometrium
Coronary artery
Dendritic (plasmacytoid) cell
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Disease Atlas
Most Correlated Diseases
Ebola virus disease
Poisoning by drug AND/OR medicinal substance
Toxic nephropathy
Social environment related disease
Vesicular stomatitis Indiana virus disease
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Pharmaco Atlas
Most Correlated Compounds
Femara
Anthracyclines
ARQ 197
Electromagnetic Radiation
sodium chromate(VI)
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Knockdown Atlas
Most Correlated Gene Perturbations
FGFR1
MRPL19
SIX6
SMAD2
AKT2
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Curated Studies
Most Correlated Studies
L1000 CMAP Prostate cancer VCaP cells with gene overexpression perturbations
Whole blood of patients with single and double primary tumors and healthy controls
L1000 CMAP Breast cancer MCF7 cells with gene overexpression perturbations
L1000 CMAP - Hepatocellular carcinoma Hep G2 cells with shRNA-mediated gene knockdown (1 of 2)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide pr…
A Flt3- and Ras-dependent pathway primes B cell development by inducing a state of IL-7 responsivene…
Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors.
Transcriptional regulation of early B-lymphocyte differentiation.
Modulation of the IL-7 dose-response threshold during pro-B cell differentiation is dependent on pre…
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Clinical Trials
Most Relevant Clinical Trials
Magseed Pro(R)/ Sentimag(R) Gen3
Study of PRO 140 for Prophylaxis of Acute GVHD in Patients Undergoing RIC Allogenic Stem-Cell Transp…
Tai-Chi-Chuan on Differentiation and Maturation of Dendritic Cells
Clinical Trial to Determinate Dose, Security and Efficacy or Lenalidomide and Rituximab (LR)-ESHAP i…
Phenotypic and Functional Characterisation of Human B-cell Response in Pemphigus
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