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Correlation Engine 2.0
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(e.g. Ischemia, Intestine, Laryngoscope, Lipopolysaccharide, rs4950928, DRD2)
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QuickView for telomere capping (biogroup)


Body Atlas

Most Correlated Tissues

  1. Basophil of peripheral blood
  2. B lymphocyte (IgM memory) of spleen
  3. Mononuclear cell of peripheral blood
  4. T Lymphocyte (CD4+) of peripheral blood
  5. T Lymphocyte (regulatory) of peripheral blood
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Disease Atlas

Most Correlated Diseases

  1. Hemorrhagic shock
  2. Abscess
  3. Vesicular stomatitis Indiana virus disease
  4. Contact dermatitis
  5. Listeriosis
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Pharmaco Atlas

Most Correlated Compounds

  1. CP 724714
  2. CGP 60474
  3. AZD1480
  4. ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)
  5. flavopiridol
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. E2f
  2. Dp
  3. PCDH11X
  4. NDRG1
  5. AURKB
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Kidney epithelial HA1E.311 cells with CRISPR targeted gene knockouts
  2. L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
  3. L1000 CMAP - Umbilical vein endothelial HUVEC cells treated with small molecule perturbagens
  4. L1000 CMAP - Skeletal muscle SKL.C cells treated with small molecule perturbagens
  5. L1000 CMAP - Neuronal NEU cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Tel1 and Rad51 are involved in the maintenance of telomeres with capping deficiency.
  2. DNA-PKcs Inhibition Sensitizes Cancer Cells to Carbon-Ion Irradiation via Telomere Capping Disruptio…
  3. Linear chromosome maintenance in the absence of essential telomere-capping proteins.
  4. Msh2 deficiency leads to chromosomal abnormalities, centrosome amplification, and telomere capping d…
  5. The Drosophila HOAP protein is required for telomere capping.
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Clinical Trials

Most Relevant Clinical Trials

  1. Low-Dose Danazol for the Treatment of Telomere Related Diseases
  2. Telomeric Abnormalities in Colorectal Diseases by Fluorescent in Situ Hybridization Technique
  3. Impact of Lifestyle Changes on Telomeric Activity in Patients With Chronic Pain
  4. Mitochondrial DNA Copy Number and Leukocyte Telomere Length as Biomarkers in Type 2 Diabetic Patient…
  5. The Association Between Telomere Length and Propofol Dose in Anesthesia-induction
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