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SWI/SNF complex
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Summary
General Info
Body Atlas
Most Correlated Tissues
Liver
Endometrium
Lung
Vena cava
Fetal brain
Explore Body Atlas Results
Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Disease due to Rotavirus
Sepsis due to Serratia
Congenital atresia of extrahepatic bile duct
Multiple-resistant Staphylococcus aureus infection
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Pharmaco Atlas
Most Correlated Compounds
COOH-terminal signal transamidase
niguldipine
temsirolimus
ARQ 197
Tie2 kinase inhibitor
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Knockdown Atlas
Most Correlated Gene Perturbations
RARRES1
HTRA1
LCP2
COL7A1
DHPS
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7.311 cells with CRISPR-induced gene knockouts
L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
GSK cancer cell line transcript profiling
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Literature
Most Relevant Literature
Different SWI/SNF complexes coordinately promote R-loop- and RAD52-dependent transcription-coupled h…
Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis.
SWI/SNF complexes and cancers.
Advances in the role of SWI/SNF complexes in tumours.
mis)-Targeting of SWI/SNF complex(es) in cancer.
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Clinical Trials
Most Relevant Clinical Trials
Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas W…
Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lym…
Finding New Targets by Proteomic Approaches (InnovRT1)
A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK28…
Phase II Study of Tazemetostat in Solid Tumors Harboring an ARID1A Mutation
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