QuickView for single strand break repair (biogroup)

Body Atlas

Most Correlated Tissues

No tissues found

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Disease Atlas

Most Correlated Diseases

1. Bacterial infection due to Bacillus
2. Hypoproteinemia
3. Microbial culture finding
4. Rhinitis
5. Infection due to Lactobacillus

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Pharmaco Atlas

Most Correlated Compounds

1. Butylhydroxybutylnitrosamine
2. Adenylate Cyclase Toxin
3. Antigen-Antibody Complex
4. LIF protein, human
5. tolcapone

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Knockdown Atlas

Most Correlated Gene Perturbations

1. NUP62
2. NRF1
3. NFIL3
4. LRP5
5. RFX2

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Curated Studies

Most Correlated Studies

1. The Immunological Genome Project - Immune cell lineage differentiation and maturation
2. Bone marrow derived macrophages infected with H. pylori
3. Mouse fibroblasts expressing the 57Bl/6 Ah-receptor vs Ahr-/-
4. RAW264.7 macrophages overexpressing Tbc1d23 and/or stimulated with LPS
5. L1000 CMAP - Breast cancer MCF7.311 cells with CRISPR-induced gene knockouts

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Literature

Most Relevant Literature

1. Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and…
2. Topoisomerase 1 and single-strand break repair modulate transcription-induced CAG repeat contraction…
3. E2F1 is involved in DNA single-strand break repair through cell-cycle-dependent upregulation of XRCC…
4. Oxidized base damage and single-strand break repair in mammalian genomes: role of disordered regions…
5. Short-patch single-strand break repair in ataxia oculomotor apraxia-1.

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Clinical Trials

Most Relevant Clinical Trials

1. Phase II Study of Niraparib in Metastatic TNBC Patients With Homologous Recombination Deficiency
2. To Evaluate and Compare p53 Epidermal Expression in Healthy Volunteers 3 Months After Treatment With…
3. Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) E…
4. DNA Repair Enzyme Signature in Head and Neck Cancer (CHEMRAD)
5. Olaparib and Radiotherapy in Head and Neck Cancer

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