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FK506 binding
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Summary
General Info
Body Atlas
Most Correlated Tissues
Pericardium
Dorsal root ganglia
Aorta
Breast tissue
Mammary gland
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Disease Atlas
Most Correlated Diseases
Bacterial septicemia
Sepsis due to Escherichia coli
Perforation of tympanic membrane
Septicemia due to Klebsiella
Listeriosis
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Pharmaco Atlas
Most Correlated Compounds
naphthalene
sitagliptin
PIK 75
Ganciclovir
Pentobarbital
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Knockdown Atlas
Most Correlated Gene Perturbations
RPIA
PROCR
NOP2
POLH
POLH
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Curated Studies
Most Correlated Studies
L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
L1000 CMAP - Neural progenitor NPC cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
L1000 CMAP - T-cell ALL JURKAT cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
NMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodiu…
Crystal structure of the FK506 binding domain of Plasmodium falciparum FKBP35 in complex with FK506.
Regulation of store-operated calcium entry by FK506-binding immunophilins.
Noncanonical FK506-binding protein BDBT binds DBT to enhance its circadian function and forms foci a…
Crystal structure and transient dimerization for the FKBP12 protein from the pathogenic fungus Candi…
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Clinical Trials
Most Relevant Clinical Trials
Biomarker Expression in Patients With ACTH-Dependent Cushing's Syndrome Before and After Surgery
Tissue Predictors of Abiraterone Benefit
The Role of Sex Steroids and Serotonin Brain Dynamics in Perinatal Mental Health
Clinical Implications of FKBP5 in Stroke
Treatment Outcome in Major Depressive Disorder
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