QuickView for protein polyubiquitination (biogroup)

Body Atlas

Most Correlated Tissues

No tissues found

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Disease Atlas

Most Correlated Diseases

1. Alpha-1-antitrypsin deficiency
2. Disorder of digestive system
3. Hemorrhagic shock
4. Injury of eye region
5. Disease due to Orthopoxvirus

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Pharmaco Atlas

Most Correlated Compounds

1. CGP 60474
2. Ions
3. dinaciclib
4. KW 2449
5. PHA 767491

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Knockdown Atlas

Most Correlated Gene Perturbations

1. PCDH11X
2. FUBP3
3. AKT2
4. PLXNA1
5. hsa-miR-365a-3p

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Curated Studies

Most Correlated Studies

1. Calu-3 lung adenocarcinoma cells infected with wildtype and mutant SARS virus
2. Neural development of iPSCs derived from Autistic patients with BCKD-kinase mutations
3. BV-2 microglial cells treated with curcumin, LPS or both treatments
4. Neuroblastoma SKNDZ cells overexpressing MIR-125-B2
5. Surface epithelia from primary ovarian carcinomas

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Literature

Most Relevant Literature

1. Protein monoubiquitination and polyubiquitination generate structural diversity to control distinct …
2. MdmX protein is essential for Mdm2 protein-mediated p53 polyubiquitination.
3. Protein polyubiquitination plays a role in basal host resistance of barley.
4. Using protein motion to read, write, and erase ubiquitin signals.
5. The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogen…

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Clinical Trials

Most Relevant Clinical Trials

1. A Phase 1 Trial of the p97 Inhibitor CB-5339 in Patients With Advanced Solid Tumors and Lymphomas
2. Muscle Wasting in Hemodialysis Patient
3. A Dose Escalation Study of MLN7243 (TAK-243) in Adult Participants With Advanced Solid Tumors

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