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Correlation Engine 2.0
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(e.g. Doxorubicin, rs2300478, FGF21, Angiogenesis, Obesity, Pancreas, Nosology)
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QuickView for double-stranded DNA binding (biogroup)


Body Atlas

Most Correlated Tissues

  1. Vestibular nuclei superior
  2. Ventral tegmental area
  3. Hippocampus
  4. Hypothalamus
  5. Substantia nigra
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Disease Atlas

Most Correlated Diseases

  1. Alpha-1-antitrypsin deficiency
  2. Disorder of digestive system
  3. Disease due to Orthopoxvirus
  4. Listeriosis
  5. Lymphedema
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Pharmaco Atlas

Most Correlated Compounds

  1. tivozanib
  2. N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
  3. CGP 60474
  4. ARQ 197
  5. KW 2449
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. DIDO1
  2. FUBP3
  3. NOP2
  4. NR5A1
  5. ANKRD2
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
  2. L1000 CMAP - Pancreatic cancer YAPC.311 cells with CRISPR-targeted gene knockouts
  3. L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
  4. L1000 CMAP - Prostate cancer PC3.101 cells with CRISPR-targeted gene knockouts
  5. L1000 CMAP - Colorectal cancer HT29.311 cells with CRISPR-targeted gene knockouts
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Literature

Most Relevant Literature

  1. Double-stranded DNA binding domain of poly(ADP-ribose) polymerase-1 and molecular insight into the r…
  2. Single- and double-stranded DNA binding proteins act in concert to conserve a telomeric DNA core seq…
  3. Synthesis, double stranded DNA-binding and photocleavage studies of a functionalized ruthenium(II) c…
  4. Structural peculiarities of the (MHF1-MHF2)4 octamer provide a long DNA binding patch to anchor the …
  5. Distinct double- and single-stranded DNA binding of E. coli replicative DNA polymerase III alpha sub…
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Clinical Trials

Most Relevant Clinical Trials

  1. Nelfinavir in Systemic Lupus Erythematosus
  2. Topical NF-kappaB Decoy in the Treatment of Atopic Dermatitis
  3. Allogenic Stem Cell Transplantation in Patients With High Risk CD33+ AML/MDS/JMML
  4. Measurement of Anti-dsDNA by Both CLIFT & ELISA
  5. A Phase II Multi-Strata Study of PM01183 as a Single Agent or in Combination With Conventional Chemo…
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