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Correlation Engine 2.0
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(e.g. T cell differentiation, HIV infection, Lung, Autoimmunity, Vitamin E, rs3825942, PDX1)
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QuickView for sequence-specific DNA binding (biogroup)


Body Atlas

Most Correlated Tissues

  1. Vestibular nuclei superior
  2. Hippocampus
  3. Substantia nigra
  4. Hypothalamus
  5. Ventral tegmental area
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Disease Atlas

Most Correlated Diseases

  1. Alpha-1-antitrypsin deficiency
  2. Disorder of digestive system
  3. Disease due to Orthopoxvirus
  4. Listeriosis
  5. Cytomegalovirus infection
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Pharmaco Atlas

Most Correlated Compounds

  1. tivozanib
  2. N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
  3. ARQ 197
  4. CGP 60474
  5. TAE226
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. DIDO1
  2. FUBP3
  3. NOP2
  4. NR5A1
  5. ANKRD2
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
  2. L1000 CMAP - Pancreatic cancer YAPC.311 cells with CRISPR-targeted gene knockouts
  3. L1000 CMAP - Prostate cancer PC3.101 cells with CRISPR-targeted gene knockouts
  4. L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
  5. Reprogramming of fibroblasts into embryonic Sertoli-like cells
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Literature

Most Relevant Literature

  1. Identification and characterization of a previously undescribed family of sequence-specific DNA-bind…
  2. An ultrasensitive label-free biosensor for assaying of sequence-specific DNA-binding protein based o…
  3. Probing the electrostatics and pharmacological modulation of sequence-specific binding by the DNA-bi…
  4. A WNT/p21 circuit directed by the C-clamp, a sequence-specific DNA binding domain in TCFs.
  5. B-Myb promotes S-phase independently of its sequence-specific DNA binding activity and interacts wit…
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Clinical Trials

Most Relevant Clinical Trials

  1. Optimising DNA Vaccinations in Healthy Volunteers
  2. Quantification of Bacterial DNA in Sepsis
  3. Sequencing Abiraterone and Enzalutamide in mCRPC
  4. Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics
  5. RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2
Explore Clinical Trials Results
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