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(e.g. Cisplatin, rs6983267, SLC12A1, Response to oxidative stress, Allergy to pollen)
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QuickView for regulation of sequence-specific DNA binding transcription factor activity (biogroup)


Body Atlas

Most Correlated Tissues

  1. Cerebral cortex
  2. Hippocampus
  3. Lung
  4. Hypothalamus
  5. Pituitary gland
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Disease Atlas

Most Correlated Diseases

  1. Alpha-1-antitrypsin deficiency
  2. Disorder of digestive system
  3. Disease due to Orthopoxvirus
  4. Disorder of lung
  5. Listeriosis
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Pharmaco Atlas

Most Correlated Compounds

  1. ARQ 197
  2. N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
  3. CGP 60474
  4. KW 2449
  5. FR 180204
Explore Pharmaco Atlas Results

Knockdown Atlas

Most Correlated Gene Perturbations

  1. PCDH11X
  2. ANKRD2
  3. TLK2
  4. FUBP3
  5. NOP2
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
  2. L1000 CMAP - Colorectal cancer HT29.311 cells with CRISPR-targeted gene knockouts
  3. L1000 CMAP - Prostate cancer PC3.101 cells with CRISPR-targeted gene knockouts
  4. L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
  5. Neuroblastoma SKNDZ cells overexpressing MIR-125-B2
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Literature

Most Relevant Literature

  1. Regulation of transcription factor activity by SUMO modification.
  2. PPAR SUMOylation: some useful experimental tips.
  3. Suppression of a MEF2-KLF6 survival pathway by PKA signaling promotes apoptosis in embryonic hippoca…
  4. Transcription Factor CHF1/Hey2 Regulates Specific Pathways in Serum Stimulated Primary Cardiac Myocy…
  5. CK2 phosphorylation of Pdx-1 regulates its transcription factor activity.
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Clinical Trials

Most Relevant Clinical Trials

  1. RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2
  2. Risk Factors of Immune-ChEckpoint Inhibitors MEdiated Liver, Gastrointestinal, Endocrine and Skin To…
  3. Epigenetic Features of FoxP3 in Children With Cow's Milk Allergy
  4. Peptide-drug-conjugates for Personalized, Targeted Therapy of Chronic Lymphocytic Leukemia
  5. Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma
Explore Clinical Trials Results
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