1Interactive help is here to guide you through BaseSpace Correlation Engine

Interactive Help contains a set of 15 succinct Training exercises that are linked one to the next. You get quick snapshots into the applications that act as a springboard for you to gain 'data driven' insights applied to your research.

Select Interactive Help next to the user icon at the top right of any page.

2Bioset pathway view

Visualize gene lists in Pathway Viewer by Elsevier and find relevant Canonical Pathways. Visually explore the interactions among your results in the context of Elsevier's literature-derived knowledgebase of published biological relationships linked to the corresponding literature..

3Biosets data filters

Filter and export features by fold change, rank and more. Narrow down your results list with the application of data filters based on custom fold changes and direction of activity. Apply cut-offs to limit results to highest ranked, strongest p-values or test and control gene activities. Filtered gene lists can be used for bioset export, to create a new bioset, or to pass onto Pathway Viewer.

4RNA-Seq platforms now supported for human, mouse, and rat

Interested in Next-Generation Sequencing analysis of gene expression in the public data-verse? Correlation Engine is now bringing in all the qualifying RNA expression by high throughput sequencing studies from the Gene Expression Omnibus. To quickly browse NGS data specifically, use the 'RNA-Seq Studies' button on the Curated Studies Quick Start page or include it as a criteria in the advanced Boolean search from the all curated studies page.

5Body Atlas: RNA-Seq gene signatures now available

Body Atlas gene signature content has been expanded to include Next-generation sequencing analysis of RNA expression in 39 normal tissues from the Genotype-Tissue Expression project (GTEx). Select between array and RNA-seq sources of data when querying for tissue expression profiles or distributions of expression of a specific gene query across tissues.

5Body Atlas: RNA-Seq gene signatures now available.

Import your RNA-Seq data to Correlation Engine. Format your data signatures using RefSeq identifiers corresponding to the human hg19 March 6 2013, mouse mm10 May 3 2014, rat rn5 May 3 2014 genome build releases and have your data tabulated as a NGS platform in Correlation Engine. Using the RefSeq identifiers will identify your platform and allow for improved correlation analysis in the Correlation Engine apps.

Correlation Engine: Explore the apps.

QuickView

Not sure where to begin? Get a comprehensive overview of everything Correlation Engine can tell you about your query term or imported dataset.

• QuickView
• Curated Studies
• Body Atlas
• Disease Atlas
• Pharmaco Atlas
• Knockdown Atlas
• Genetic Markers
• Biogroups
• Literature
• Clinical Trials

Correlation Engine: Explore the apps.

Curated Studies

Access our continuously growing library of curated public genomic data. Query this app to see how your query term or imported dataset correlate with thousands of curated public studies.

• QuickView
• Curated Studies
• Body Atlas
• Disease Atlas
• Pharmaco Atlas
• Knockdown Atlas
• Genetic Markers
• Biogroups
• Literature
• Clinical Trials

Correlation Engine: Explore the apps.

Body Atlas

Compare gene expression levels across hundreds of human and mouse tissues, cell types, cell lines, and stem cells.

• QuickView
• Curated Studies
• Body Atlas
• Disease Atlas
• Pharmaco Atlas
• Knockdown Atlas
• Genetic Markers
• Biogroups
• Literature
• Clinical Trials

Correlation Engine: Explore the apps.

Disease Atlas

Find diseases that are significantly correlated to a gene or imported dataset.

• QuickView
• Curated Studies
• Body Atlas
• Disease Atlas
• Pharmaco Atlas
• Knockdown Atlas
• Genetic Markers
• Biogroups
• Literature
• Clinical Trials

Correlation Engine: Explore the apps.

Pharmaco Atlas

Discover drugs and compounds whose genetic signature includes a particular gene or is enriched in an imported dataset.

• QuickView
• Curated Studies
• Body Atlas
• Disease Atlas
• Pharmaco Atlas
• Knockdown Atlas
• Genetic Markers
• Biogroups
• Literature
• Clinical Trials

Correlation Engine: Explore the apps.

Knockdown Atlas

Perform knockdown, knockout, or overexpression experiments in reverse: See which genetic perturbations affect a gene or imported dataset, and how.

• QuickView
• Curated Studies
• Body Atlas
• Disease Atlas
• Pharmaco Atlas
• Knockdown Atlas
• Genetic Markers
• Biogroups
• Literature
• Clinical Trials

Correlation Engine: Explore the apps.

Genetic Markers

Discover genes & SNPs found to be significant across multiple studies of a disease, compound, or tissue.

• QuickView
• Curated Studies
• Body Atlas
• Disease Atlas
• Pharmaco Atlas
• Knockdown Atlas
• Genetic Markers
• Biogroups
• Literature
• Clinical Trials

Correlation Engine: Explore the apps.

Biogroups

Find pathways, molecular functions, protein families, and biological processes that involve a gene or are enriched in an imported dataset.

• QuickView
• Curated Studies
• Body Atlas
• Disease Atlas
• Pharmaco Atlas
• Knockdown Atlas
• Genetic Markers
• Biogroups
• Literature
• Clinical Trials

Correlation Engine: Explore the apps.

Literature

Do a classic PubMed literature search, or search hundreds of biology- and health-related news sources.

• QuickView
• Curated Studies
• Body Atlas
• Disease Atlas
• Pharmaco Atlas
• Knockdown Atlas
• Genetic Markers
• Biogroups
• Literature
• Clinical Trials

Correlation Engine: Explore the apps.

Clinical Trials

Find clinical trials that interest you (including actively recruiting studies).

• QuickView
• Curated Studies
• Body Atlas
• Disease Atlas
• Pharmaco Atlas
• Knockdown Atlas
• Genetic Markers
• Biogroups
• Literature
• Clinical Trials