Allogeneic peripheral blood stem cell transplant (PBSCT) using anti-IL2 receptor antibody Daclizumab for the prevention of acute graft versus host disease in steroid refractory Diamond Blackfan anaemia: a case report.

Tahir Sultan Shamsi, Mohammad Irfan, Tasneem Farzana, Saqib Hussain Ansari, Ghazala Ahmad, Nazmeen Shakoor, Mirza Irfan Baig

Bismillah Taqee Institute of Health Sciences and Blood Diseases Centre, Karachi, Pakistan.

JPMA. The Journal of the Pakistan Medical Association 2005 Oct

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The case report of a 2 year old boy with steroid refractory DBA, treated with allogeneic PBSCT from an HLA matched sibling is presented. Anti-IL2 receptor antibody Daclizumab was used as a prophylaxis for graft versus host disease (GvHD). Complete recovery without any evidence of GvHD ensued.

Citation

Tahir Sultan Shamsi, Mohammad Irfan, Tasneem Farzana, Saqib Hussain Ansari, Ghazala Ahmad, Nazmeen Shakoor, Mirza Irfan Baig. Allogeneic peripheral blood stem cell transplant (PBSCT) using anti-IL2 receptor antibody Daclizumab for the prevention of acute graft versus host disease in steroid refractory Diamond Blackfan anaemia: a case report. JPMA. The Journal of the Pakistan Medical Association. 2005 Oct;55(10):454-5