Part VII. Macrolides, azalides, ketolides, lincosamides, and streptogramins.

Van Dang, Neha Nanda, Travis W Cooper, Ronald A Greenfield, Michael S Bronze

Infectious Diseases Section, PO Box 26901, WP 1160. Oklahoma City, OK 73190, USA.

The Journal of the Oklahoma State Medical Association 2007 Mar

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In this article we describe antimicrobials that are grouped by their similar mechanism of action, namely inhibition of protein synthesis at the bacterial 50S ribosomal subunit. Macrolides, azalides, and ketolides are primarily used to treat community acquired respiratory tract infections. A lincosamide antibiotic, clindamycin, is primarily used to treat anaerobic infections. A combination of streptogramins, quinupristin/dalfopristin, is used to treat infections due to multiple drug resistant Gram positive cocci.

Citation

Van Dang, Neha Nanda, Travis W Cooper, Ronald A Greenfield, Michael S Bronze. Part VII. Macrolides, azalides, ketolides, lincosamides, and streptogramins. The Journal of the Oklahoma State Medical Association. 2007 Mar;100(3):75-81