Effect of PTSD diagnosis and contingency management procedures on cocaine use in dually cocaine- and opioid-dependent individuals maintained on LAAM: a retrospective analysis.

Michael J Mancino, Janette McGaugh, Zachary Feldman, James Poling, Alison Oliveto

Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. mjmancino@uams.edu

The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions 2010 Mar-Apr

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This randomized clinical trial retrospectively examined the effect of post-traumatic stress disorder (PTSD) and contingency management (CM) on cocaine use in opioid and cocaine dependent individuals maintained on high or low-dose LAAM randomly assigned to CM or a yoked-control condition. Cocaine-positive urines decreased more rapidly over time in those without PTSD versus those with PTSD in the noncontingency condition. In participants with PTSD, CM resulted in fewer cocaine-positive urines compared to the noncontingent condition. This suggests that CM may help improve the potentially worse outcomes in opioid- and cocaine-dependent individuals with PTSD compared to those without PTSD. (Am J Addict 2010;00:1-9).

Citation

Michael J Mancino, Janette McGaugh, Zachary Feldman, James Poling, Alison Oliveto. Effect of PTSD diagnosis and contingency management procedures on cocaine use in dually cocaine- and opioid-dependent individuals maintained on LAAM: a retrospective analysis. The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions. 2010 Mar-Apr;19(2):169-77