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Venlafaxine is an antidepressant which blocks reuptake of noradrenaline and serotonin and, to a lesser extent, dopamine. These data have been confirmed by behavioral tests. It has been shown that by decreasing the overall cerebral quantity of 5-HT and NA, venlafaxine continued to have an antidepressant action in animal models. In addition, the drug has been shown to act preferentially on 5-HT1A and 5-HT1B receptors.
Citation
M Bourin. Psychopharmacological profile of venlafaxine]. L'Encéphale. 1999 Jun;25 Spec No 2:21-2; discussion 23-5
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PMID: 10434156
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