Clinical roles of vitamins in hematopoietic disorders].

M Matsuda, A Kanamaru

Third Department of Internal Medicine, Kinki University School of Medicine.

Nihon rinsho. Japanese journal of clinical medicine 1999 Oct

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Vitamins are essential organisms which promote various metabolisms and physiological systems. Several vitamins play important roles in hematopoietic system. Vitamin B12, C and folic acid are associated with DNA synthesis of erythroid nucleus, the deficiency of which causes the megaloblastic anemia. Some megaloblatic anemia and sideroblastic anemia might response to vitamin B1 and B6, respectively. Vitamin K participates in some coagulation factors in coagulation-fibrinogenolysis system. It has been reported that vitamins A, D and K potentially differentiate leukemic cells and then induce the apoptosis, suggesting that they would be new therapeutic agents in acute leukemia.

Citation

M Matsuda, A Kanamaru. Clinical roles of vitamins in hematopoietic disorders]. Nihon rinsho. Japanese journal of clinical medicine. 1999 Oct;57(10):2349-55