College of Pharmacy, Sookmyung Women's University, Seoul 140-742, Korea. ryuha@sdic.sookmyung.ac.kr
Journal of natural products 1999 OctA new bisabolene epoxide was isolated from the flower buds of Tussilago farfara, and the structure was determined by spectroscopic methods to be 1alpha,5alpha-bisacetoxy-8-angeloyloxy-3beta, 4beta-epoxy-bisabola-7(14),10-dien-2-one (1). Compound 1 showed inhibition of nitric oxide synthesis in lipopolysaccharide-activated macrophages.
J H Ryu, Y S Jeong, D H Sohn. A new bisabolene epoxide from Tussilago farfara, and inhibition of nitric oxide synthesis in LPS-activated macrophages. Journal of natural products. 1999 Oct;62(10):1437-8
PMID: 10543912
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