Treatment of infectious complications of experimental acute radiation injury with combined antibiotic sulacillin].

K S Chertkov, E A Revskaia

State Research Centre of Russia-Institute of Biophysics, Moscow. ibphgen@rcibph.dol.ru

Radiatsionnaia biologiia, radioecologiia / Rossiĭskaia akademiia nauk 1999 Sep-Oct

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An anti-infectious effect of sulacillin (ampicillin/sulbactam) is higher than that of ampicillin in treatment of irradiated mice infected with a beta-lactamaseproducing strain of Kl. pneumoniae. Involving of sulacillin as a principal antibiotic into the therapeutic scheme for acute radiation sickness results in 67% dogs survival at LD90/45.

Citation

K S Chertkov, E A Revskaia. Treatment of infectious complications of experimental acute radiation injury with combined antibiotic sulacillin]. Radiatsionnaia biologiia, radioecologiia / Rossiĭskaia akademiia nauk. 1999 Sep-Oct;39(5):568-71