Current approach to the treatment of acute bronchial asthma].

Terapevticheskiĭ arkhiv 2000

To evaluate the results of nebulised berodual solution in comparison with intravenous euphylline in the treatment of acute bronchial asthma (BA). The trial entered 73 patients with an acute episode of BA: 22 treated with intravenous euphylline and 51 treated with nebulised berodual solution. Spirometry was conducted and peak expiratory flow rate, heart rate (HR), blood pressure were measured before and after the treatment. The attack was arrested in all the patients who had inhaled nebulised berodual solution. No side effects were registered. Intravenous therapy of euphylline produced only partial bronchodilation in most of the patients and increased HR by 23.4%. Berodual nebulised solution is clinically superior to intravenous euphylline in acute BA.