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2-Hydroxyethyl) dimethylsulfoxonium chloride (1), the well-known causative agent of Dogger Bank Itch, has been isolated as a cytotoxic constituent from the marine sponge Theonella aff. mirabilis. The structure of 1 was determined by spectral and X-ray crystallographic analyses.

Citation

K Warabi, Y Nakao, S Matsunaga, T Fukuyama, T Kan, S Yokoshima, N Fusetani. Dogger Bank Itch revisited: isolation of (2-hydroxyethyl) dimethylsulfoxonium chloride as a cytotoxic constituent from the marine sponge Theonella aff. mirabilis. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2001 Jan;128(1):27-30

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PMID: 11163301

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