Conformation of 1,4-dineopentyl-2,5-cis-diphenylpiperazine and its diammonium salts: remarkable change in conformation depending upon the counter anion.

K Takasu, K Tanaka, K Fuji

Institute for Chemical Research, Kyoto University, Uji, Japan.

Chemical & pharmaceutical bulletin 2001 May

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The free base of 1,4-dineopentyl-2,5-diphenylpiperazine takes a chair conformation in CDCl3, while the conformation of its diammonium salts changes depending upon the counter anion.

Citation

K Takasu, K Tanaka, K Fuji. Conformation of 1,4-dineopentyl-2,5-cis-diphenylpiperazine and its diammonium salts: remarkable change in conformation depending upon the counter anion. Chemical & pharmaceutical bulletin. 2001 May;49(5):655-6