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We describe a 74-year-old patient with dyspnoea and tachypnoea induced by chlorpromadinone acetate, a synthetic progesterone used to treat prostatic hyperplasia. The dyspnoea, tachypnoea and hypocapnia improved after discontinuing the chlorpromadinone acetate. It is important to recognize that synthetic progesterones can cause dyspnoea and hyperventilation.


K Fujii, H Kohrogi, S Hirosako, O Kawano, N Hirata, E Goto, M Ando. Dyspnoea and hyperventilation induced by synthetic progesterone chlorpromadinone acetate for the treatment of prostatic hypertrophy. Respirology (Carlton, Vic.). 2001 Sep;6(3):265-7

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PMID: 11555387

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