Diagnostic significance of albumin transporting characteristics and blood level of troponin T in myocardial infarction].

V N Titov, I I Staroverov, V A Ameliushkina, Iu A Gryzunov, M B Filipenko, M G Tvorogova, G E Dobretsov

Klinicheskaia laboratornaia diagnostika 2002 Jan

filter terms:

Serum albumin binding capacity (ABC) was studied using K-35 hydrophobic fluorescent probe in order evaluate the passive transfer and absorption of saturated fatty acids (s-FA) by the cells. ABC decreases on day 3 of myocardial infarction and remains low till discharge and is paralleled by hyperTG. We believe that ABC decrease reflects activation of passive transfer and absorption of s-FA by the cells during simultaneous blocking (presumably by acute phase proteins) of active apoE/B-100 receptor endocytosis of s-FA in the form of TG as VLDL remnants. Decrease of ABC reflects a later than erythrocyte sedimentation rate and acute phase proteins normalization of metabolic consequences of inflammation. ABC helps indirectly evaluate the blocking of active (receptor) absorption of s-FA in the form of TG and activation of passive absorption of s-FA from associations with albumin by the cells.

Citation

V N Titov, I I Staroverov, V A Ameliushkina, Iu A Gryzunov, M B Filipenko, M G Tvorogova, G E Dobretsov. Diagnostic significance of albumin transporting characteristics and blood level of troponin T in myocardial infarction]. Klinicheskaia laboratornaia diagnostika. 2002 Jan(1):3-7