Juan F Sanz-Cervera, Robert M Williams
Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA.
Journal of the American Chemical Society 2002 Mar 20The first asymmetric biomimetic total synthesis of VM55599 (13) has been achieved utilizing an intramolecular Diels-Alder cycloaddition as a key step. The synthetic material was utilized to elucidate the absolute stereochemistry of the natural product. The results are discussed in terms of a unified biogenesis of the paraherquamides and VM55599.
Juan F Sanz-Cervera, Robert M Williams. Asymmetric total synthesis of (-)-VM55599: establishment of the absolute stereochemistry and biogenetic implications. Journal of the American Chemical Society. 2002 Mar 20;124(11):2556-9
PMID: 11890806
View Full Text