The role of the caudate nucleus in the development of convulsive discharges].

R M Avakian, E B Arushanian

Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova 1975 Apr

filter terms:

A single or rhythmical (1-3/sec) stimulation of the caudate nucleus in unrestrained rats facilitated formation of slow negative waves and the spike-wave complexes in the EEG of the sensory-motor cortex and contralateral neostriatum, as well as development of behavioral disturbances due to subseisure doses of pentylentetrazol. During the low-frequency stimulation of the caudate nucleus or after its cessation, when giving the convulsant drug, regular potentials of the spike-wave type or a general seizure may occur. The caudate nucleus is supposed to be able to participate in the petit mal seizure mechanisms because of its syndhronizing influences on the cortex.

Citation

R M Avakian, E B Arushanian. The role of the caudate nucleus in the development of convulsive discharges]. Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova. 1975 Apr;61(4):480-7