Ulf Reimer, Ulrich Reineke, Jens Schneider-Mergener
Jerini AG, Invalidenstrasse 130, D-10115 Berlin, Germany. reimer@jerini.com
Current opinion in biotechnology 2002 AugOver the past decade of proteome research peptide arrays have become a widespread and powerful tool to study molecular recognition events and to identify biologically active peptides. A variety of applications such as epitope mapping, characterisation of protein-protein interactions, enzyme-substrate or inhibitor interactions, and many more, have been published. Today's technologies for array production, inspired by DNA chips, have recently turned to the miniaturisation of peptide arrays. These advances open up an expanding spectrum of applications and the information obtained will be well-suited to developing substrates and inhibitors for diagnostic and therapeutic purposes.
Ulf Reimer, Ulrich Reineke, Jens Schneider-Mergener. Peptide arrays: from macro to micro. Current opinion in biotechnology. 2002 Aug;13(4):315-20
PMID: 12323352
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