Alkaloids from Menispermum dauricum.

Bing-Wu Yu, Jian-Yong Chen, Yan-Ping Wang, Kin-Fin Cheng, Xiao-Yu Li, Guo-Wei Qin

Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, People's Republic of China.

Phytochemistry 2002 Oct

filter terms:

The alkaloids, dechloroacutumidine and 1-epidechloroacutumine, together with three known alkaloids, acutumidine, acutumine, and dechloroacutumine, were isolated from the rhizomes of Menispermum dauricum and their structures established by spectral and chemical methods. The cytotoxicity of each compound against the growth of human cell lines was studied, and acutumine selectively inhibited T-cell growth.

Citation

Bing-Wu Yu, Jian-Yong Chen, Yan-Ping Wang, Kin-Fin Cheng, Xiao-Yu Li, Guo-Wei Qin. Alkaloids from Menispermum dauricum. Phytochemistry. 2002 Oct;61(4):439-42