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Synthesis of lipid A type carboxymethyl derivatives having ether chains at both the C-3 and C-3' positions and their LPS-antagonistic activities toward human U937 cells are described.

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Yukiko Watanabe, Kumiko Miura, Masao Shiozaki, Saori Kanai, Shin ichi Kurakata, Masahiro Nishijima. Synthesis of lipid A type carboxymethyl derivatives with ether chains instead of ester chains and their LPS-antagonistic activities. Carbohydrate research. 2003 Jan 2;338(1):47-54

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PMID: 12504380

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