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Synthesis of (-)-TAN-2483A. Revision of the structures and syntheses of (+/-)-FD-211 (waol A) and (+/-)-FD-212 (waol B).
Xiaolei Gao, Masakazu Nakadai, Barry B Snider
Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454-9110, USA.
Organic letters 2003 Feb 20Sizes of these terms reflect their relevance to your search.
structure: see text] The structure of waol A has been revised from 1 to 6, the vinylogue of TAN-2483 A (5). Aldol reaction of 10b(c) with 2,4-hexadienal (11) affords 9b(c), which is subjected to iodoetherification with bis(sym-collidine)IPF(6) to provide 8b(c). Treatment with Et(3)N in CH(2)Cl(2) completes three-step syntheses of TAN-2483A (5) and waol A (6).
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Xiaolei Gao, Masakazu Nakadai, Barry B Snider. Synthesis of (-)-TAN-2483A. Revision of the structures and syntheses of (+/-)-FD-211 (waol A) and (+/-)-FD-212 (waol B). Organic letters. 2003 Feb 20;5(4):451-4
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PMID: 12583741
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