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Primary liposarcoma of the thyroid gland is extremely rare with only two previous reports in the literature. We report two further cases, both patients presenting with rapid airways compression. Patient 1 had clinical, radiographic, and biopsy appearances suggesting benign goiter. Patient 2 had a long-term history of benign goiter, a previous partial thyroidectomy, and more recent biopsies showing liposarcoma. The management of such rare conditions is always challenging.

Citation

Wael I Awad, Peter H Rhys Evans, Andrew G Nicholson, Peter Goldstraw. Liposarcoma of the thyroid gland mimicking retrosternal goiter. The Annals of thoracic surgery. 2003 Feb;75(2):566-8

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PMID: 12607674

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