More kapakahines from the marine sponge Cribrochalina olemda.

Yoichi Nakao, Jacqueline Kuo, Wesley Y Yoshida, Michelle Kelly, Paul J Scheuer

Department of Chemistry, University of Hawai'i at Manoa, 2545 The Mall, Honolulu, Hawaii 96822-2275, USA. ayocha@mail.ecc.u-tokyo.ac.jp

Organic letters 2003 May 1

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Three new kapakahines E-G (1-3) have been isolated from the marine sponge Cribrochalina olemda. Limited quantities of these compounds required not only NMR analysis but also FAB-MS/MS analysis for the structure elucidation. Kapakahine E showed cytotoxicity against P388 murine leukemia cells. [structure: see text]

Citation

Yoichi Nakao, Jacqueline Kuo, Wesley Y Yoshida, Michelle Kelly, Paul J Scheuer. More kapakahines from the marine sponge Cribrochalina olemda. Organic letters. 2003 May 1;5(9):1387-90