Eudesmane derivatives from Laggera pterodonta.

Yecheng Xiao, Qunxiong Zheng, Qijun Zhang, Handong Sun, Françoise Guéritte, Yu Zhao

Department of Traditional Chinese Medicine and Natural Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, China.

Fitoterapia 2003 Jul

filter terms:

A new eudesmane derivative, 4alpha,5alpha-dihydroxyeudesma-11(13)-en-12-oic acid, was isolated from Laggera pterodonta. Its structure was elucidated as (1) on the basis of spectroscopic evidence. Moreover, six known compounds were isolated: pterodontriol A (2), pterodontriol B, pterodonta acid (3), ilicic acid (4), costic acid and beta-amyrin. Cytotoxic activity of compounds 2, 3 and 4 was investigated.

Citation

Yecheng Xiao, Qunxiong Zheng, Qijun Zhang, Handong Sun, Françoise Guéritte, Yu Zhao. Eudesmane derivatives from Laggera pterodonta. Fitoterapia. 2003 Jul;74(5):459-63