Characterization of DIP1, a novel nuclear protein in Drosophila melanogaster.

Bruna De Felice, Robert Roy Wilson, Paolo Mondola, Gianfranco Matrone, Simona Damiano, Corrado Garbi, Luigi Nezi, Tin Tin Su

Department of Life Sciences, University of Naples II, Caserta, Italy. bruna.defelice@unina2.it

Biochemical and biophysical research communications 2003 Jul 25

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We have recently identified in Drosophila melanogaster a new gene encoding a nuclear protein, DIP1. Here we report the developmental expression and the finding that DIP1 subcellular localization is in the nucleus and at the nuclear periphery during interphase in embryos. Interestingly, in humans, DIP1 antibody identified signals in nuclei from cultured cells and reacted with a rough 30kDa protein in Western blotting experiments, demonstrating evolutionary conservation.

Citation

Bruna De Felice, Robert Roy Wilson, Paolo Mondola, Gianfranco Matrone, Simona Damiano, Corrado Garbi, Luigi Nezi, Tin Tin Su. Characterization of DIP1, a novel nuclear protein in Drosophila melanogaster. Biochemical and biophysical research communications. 2003 Jul 25;307(2):224-8