Expressions of chloride channel ClC-2 and ClC-3 in human nasal polyps].
Huabin Li, Demin Han, Bing Zhou, Erzhong Fan, Zhongyan Liu
Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing Institute of Otolaryngology, Beijing 100005.
Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 2003 MayTo investigate the role of chloride channel ClC-2 and ClC-3 in human nasal polyps. Two chloride channels ClC-2 and ClC-3 were studied in 27 cases of nasal polyps with immunochemistric staining. Nasal polyps revealed strong positive staining of ClC-2 and ClC-3, the ClC-2 and ClC-3 proteins localized mainly in epithelial cells, sub-epithelial mucous glands without significant distinction. The number of positive cells of ClC-2 and ClC-3 are 17.6 +/- 6.33 and 23.49 +/- 6.14. The chloride channels ClC-2 and ClC-3 may play a role in the formation of nasal polyps.
Citation
Huabin Li, Demin Han, Bing Zhou, Erzhong Fan, Zhongyan Liu. Expressions of chloride channel ClC-2 and ClC-3 in human nasal polyps]. Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology. 2003 May;17(5):266-7
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PMID: 12916350
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