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In a controlled study (the control group receiving pyribenzamine) it was observed that reserpine, in the dosage used, had no effect on weight loss in patients receiving d-amphetamine sulphate (Dexedrine(R)) and methyl cellulose (Cellothyl(R)) while on 1,000-calorie diets as compared with the control group. There was no observable difference in subjective feelings of the patients in the two groups. Reserpine had no effect on the length of time the patients remained on their diets.

Citation

M C SMITH. Reserpine in weight reduction. The effect in obese patients on 1,000-calorie diets: a controlled study. California medicine. 1959 Oct;91:212-3

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PMID: 13832087

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