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Further chemical investigation of the stem bark of Aglaia cordata has led to the isolation and identification of three new lignans, namely, aglacins I-K (1-3), all of which contain two contiguous trimethoxylated phenyl systems. Among them, aglacins I and J (1 and 2) are new members of the aryltetralin cyclic lactol class, while aglacin K (3) is a new example of tetrahydrofuran lignan. The structures of these compounds were established on the basis of spectroscopic data interpretation.


Bin-Gui Wang, Rainer Ebel, Chang-Yun Wang, Ru Angelie Edrada, Victor Wray, Peter Proksch. Aglacins I-K, three highly methoxylated lignans from Aglaia cordata. Journal of natural products. 2004 Apr;67(4):682-4

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PMID: 15104504

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