Eki2 is upregulated specifically in the testis during mouse sex determination.

Tanya M Hurley, Peter J McClive, Mai A Sarraj, Andrew H Sinclair

Murdoch Children's Research Institute, Centre for Hormone Research, Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Melbourne, Vic 3052, Australia.

Gene expression patterns : GEP 2004 Mar

filter terms:

We have identified a gene with gonad restricted expression throughout mouse development, which is orthologous to human EKI2 (ethanolamine kinase 2). Our studies showed that mouse Eki2 expression became upregulated in the male gonad during the period of sex determination. Expression was restricted to the Sertoli cells of the developing testis. Eki2 has sequence similarity to ethanolamine (73%) and choline kinases (54%).

Citation

Tanya M Hurley, Peter J McClive, Mai A Sarraj, Andrew H Sinclair. Eki2 is upregulated specifically in the testis during mouse sex determination. Gene expression patterns : GEP. 2004 Mar;4(2):135-40