New monoterpene glucoside from the aerial parts of thyme (Thymus vulgaris L.).

Hiroyuki Takeuchi, Zhan-Guo Lu, Tomoyuki Fujita

Research and Development Laboratories, Nippon Terpene Chemicals, Inc, Kobe, Japan. takeuchi@nipponterpene.co.jp

Bioscience, biotechnology, and biochemistry 2004 May

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A new monoterpene glucoside (1) was isolated from a methanol extract of the dried aerial parts of thyme (Thymus vulgaris L.), together with known 2- and 5-beta-D-glucopyranosylthymoquinols (2 and 3, respectively), and (-)-angelicoidenol-beta-D-glucopyranoside (4). The structure of 1 was elucidated to be (R)-p-cymen-9-yl beta-D-glucopyranoside by spectral evidence and enantioselective synthesis from (R)- and (S)-p-cymen-9-ol derived from p-cymen-8-ol.

Citation

Hiroyuki Takeuchi, Zhan-Guo Lu, Tomoyuki Fujita. New monoterpene glucoside from the aerial parts of thyme (Thymus vulgaris L.). Bioscience, biotechnology, and biochemistry. 2004 May;68(5):1131-4