Correlation Engine 2.0
Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

Six furanocembranolides (1-6) and one pseudopterolide (7) have been isolated from the octocorals Leptogorgia alba and Leptogorgia rigida, collected on the Pacific coast of Panama. Compound 1, named leptolide, has a new structure closely related to the neurotoxin lophotoxin (3). The X-ray structures of 1-3 were determined, and the absolute configurations of 2-7 are discussed. Compounds 1-7 were evaluated in vitro against drug-resistant Plasmodium falciparum.


Marcelino Gutiérrez, Todd L Capson, Héctor M Guzmán, José González, Eduardo Ortega-Barría, Emilio Quiñoá, Ricardo Riguera. Leptolide, a new furanocembranolide diterpene from Leptogorgia alba. Journal of natural products. 2005 Apr;68(4):614-6

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 15844963

View Full Text