A perspective on regulation of cell-cell adhesion and epithelial-mesenchymal transition: known and novel.

Division of Human Immunology, Hanson Institute, Institute of Medical and Veterinary Science, Adelaide, Australia. yeesim.khew-goodall@imvs.sa.gov.au

Cells, tissues, organs 2005

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A number of recent reviews in the field have described many of the known growth factors and signalling pathways that may be involved in regulating epithelial-mesenchymal transitions. This perspective will focus on some aspects of posttranslational regulation of cell-cell adhesion that are less well understood and their potential role in initiating epithelial-mesenchymal transitions. In addition, a potential novel intermediate in the signalling pathway of epithelial-mesenchymal transition will also be described.

Citation

Yeesim Khew-Goodall, Carol Wadham. A perspective on regulation of cell-cell adhesion and epithelial-mesenchymal transition: known and novel. Cells, tissues, organs. 2005;179(1-2):81-6