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Template-directed single nucleotide extension of an RNA primer with oxyazabenzotriazolides of ribonucleotides is shown to be fast and sequence-selective; downstream-binding RNA strands contribute to the acceleration of the reaction.


Stephanie R Vogel, Christopher Deck, Clemens Richert. Accelerating chemical replication steps of RNA involving activated ribonucleotides and downstream-binding elements. Chemical communications (Cambridge, England). 2005 Oct 21(39):4922-4

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PMID: 16205800

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