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We report three cases of polymorphous adenocarcinoma (PLA) of the breast in 37-, 55- and 74-year-old women, respectively. The patients have no evidence of previous malignancy. The tumours consist of monotonous cells showing a wide spectrum of growth patterns: solid nests, trabeculae, tubules, cribriform structures, strands and fascicles reminiscent of polymorphous low-grade adenocarcinoma of salivary glands. To our knowledge, PLA has never been reported in the breast; therefore, this tumour should be added to the list of neoplastic lesions of the breasts that have the same features as those of the salivary glands.

Citation

Sofia Asioli, Gianluca Marucci, Guido Ficarra, Mark Stephens, Maria P Foschini, Ian O Ellis, Vincenzo Eusebi. Polymorphous adenocarcinoma of the breast. Report of three cases. Virchows Archiv : an international journal of pathology. 2006 Jan;448(1):29-34

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PMID: 16220292

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