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reaction: see text] A new tethered macrocyclic ring system based on the natural product westiellamide was prepared to increase the affinity and ease of complexation to Ag(I) ions. NMR and fluorescence Ag(I) titrations confirmed that the tethered macrocycles preserve the unique, high-affinity coordination mode of westiellamide.

Citation

Peter Wipf, Chenbo Wang. Synthesis and Ag(I) complexation studies of tethered westiellamide. Organic letters. 2006 May 25;8(11):2381-4

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PMID: 16706531

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