Observation of DNA conformation changes by energy dissipation measurements on a quartz-crystal oscillator.

Hiroyuki Furusawa, Tomomitsu Ozeki, Yoshio Okahata

Department of Biomolecular Engineering, Frontier Collaborative Research Center, Tokyo Institute of Technology and CREST, Japan Science and Technology Corporation (JST), 4259 Nagatsuta, Midori-ku, Yokohama 226-8501, Japan.

Nucleic acids symposium series (2004) 2006

filter terms:

We developed the quartz-crystal oscillator coupled with an admittance analysis to obtain viscoelastic properties and hydration amounts of dsDNA in aqueous solutions. By using this technique, we found that dsDNA became elastic and dehydrated when dsDNA formed a compact structure by the addition of multivalent cations Co(NH(3))(6)(3+) in aqueous solutions.

Citation

Hiroyuki Furusawa, Tomomitsu Ozeki, Yoshio Okahata. Observation of DNA conformation changes by energy dissipation measurements on a quartz-crystal oscillator. Nucleic acids symposium series (2004). 2006(50):321-2